diff --git chrome/browser/net/profile_network_context_service.cc chrome/browser/net/profile_network_context_service.cc
index 44ce8ba980a6..1dbbf0aa2341 100644
--- chrome/browser/net/profile_network_context_service.cc
+++ chrome/browser/net/profile_network_context_service.cc
@@ -18,6 +18,7 @@
 #include "base/strings/string_split.h"
 #include "base/task/post_task.h"
 #include "base/task/thread_pool.h"
+#include "cef/libcef/features/features.h"
 #include "chrome/browser/browser_process.h"
 #include "chrome/browser/content_settings/cookie_settings_factory.h"
 #include "chrome/browser/content_settings/host_content_settings_map_factory.h"
@@ -681,9 +682,22 @@ ProfileNetworkContextService::CreateNetworkContextParams(
   network_context_params->cookie_manager_params =
       CreateCookieManagerParams(profile_, *cookie_settings_);
 
+  network_context_params->cookieable_schemes = profile_->GetCookieableSchemes();
+
   // Configure on-disk storage for non-OTR profiles. OTR profiles just use
   // default behavior (in memory storage, default sizes).
   if (!in_memory) {
+#if BUILDFLAG(ENABLE_CEF)
+    PrefService* prefs = profile_->GetPrefs();
+    // Configure the HTTP cache path and size.
+    const base::FilePath& base_cache_path =
+        prefs->GetFilePath(prefs::kDiskCacheDir);
+    DCHECK(!base_cache_path.empty());
+    network_context_params->http_cache_path =
+        base_cache_path.Append(chrome::kCacheDirname);
+    network_context_params->http_cache_max_size =
+        prefs->GetInteger(prefs::kDiskCacheSize);
+#else
     PrefService* local_state = g_browser_process->local_state();
     // Configure the HTTP cache path and size.
     base::FilePath base_cache_path;
@@ -696,6 +710,7 @@ ProfileNetworkContextService::CreateNetworkContextParams(
         base_cache_path.Append(chrome::kCacheDirname);
     network_context_params->http_cache_max_size =
         local_state->GetInteger(prefs::kDiskCacheSize);
+#endif
 
     // Currently this just contains HttpServerProperties, but that will likely
     // change.
diff --git chrome/browser/profiles/profile.h chrome/browser/profiles/profile.h
index ee2f1e1baf51..4d53c655d723 100644
--- chrome/browser/profiles/profile.h
+++ chrome/browser/profiles/profile.h
@@ -375,6 +375,11 @@ class Profile : public content::BrowserContext {
   virtual bool ShouldRestoreOldSessionCookies();
   virtual bool ShouldPersistSessionCookies();
 
+  // Returns schemes that should be cookieable, if other than the defaults.
+  virtual base::Optional<std::vector<std::string>> GetCookieableSchemes() {
+    return base::nullopt;
+  }
+
   // Creates NetworkContext for the specified isolated app (or for the profile
   // itself, if |relative_path| is empty).
   virtual mojo::Remote<network::mojom::NetworkContext> CreateNetworkContext(
diff --git net/cookies/cookie_monster.cc net/cookies/cookie_monster.cc
index 783485c013df..bf115fd4d63a 100644
--- net/cookies/cookie_monster.cc
+++ net/cookies/cookie_monster.cc
@@ -476,6 +476,25 @@ void CookieMonster::SetCookieableSchemes(
   MaybeRunCookieCallback(std::move(callback), true);
 }
 
+void CookieMonster::AddCookieableSchemes(
+    const std::vector<std::string>& schemes,
+    SetCookieableSchemesCallback callback) {
+  DCHECK(thread_checker_.CalledOnValidThread());
+
+  // Calls to this method will have no effect if made after a WebView or
+  // CookieManager instance has been created.
+  if (initialized_) {
+    MaybeRunCookieCallback(std::move(callback), false);
+    return;
+  }
+
+  if (!schemes.empty()) {
+    cookieable_schemes_.insert(cookieable_schemes_.begin(), schemes.begin(),
+                               schemes.end());
+  }
+  MaybeRunCookieCallback(std::move(callback), true);
+}
+
 // This function must be called before the CookieMonster is used.
 void CookieMonster::SetPersistSessionCookies(bool persist_session_cookies) {
   DCHECK(thread_checker_.CalledOnValidThread());
diff --git net/cookies/cookie_monster.h net/cookies/cookie_monster.h
index 431fab884a5f..eeed129b49f2 100644
--- net/cookies/cookie_monster.h
+++ net/cookies/cookie_monster.h
@@ -180,6 +180,8 @@ class NET_EXPORT CookieMonster : public CookieStore {
   CookieChangeDispatcher& GetChangeDispatcher() override;
   void SetCookieableSchemes(const std::vector<std::string>& schemes,
                             SetCookieableSchemesCallback callback) override;
+  void AddCookieableSchemes(const std::vector<std::string>& schemes,
+                            SetCookieableSchemesCallback callback) override;
 
   // Enables writing session cookies into the cookie database. If this this
   // method is called, it must be called before first use of the instance
diff --git net/cookies/cookie_store.h net/cookies/cookie_store.h
index 996ad7d14dfb..5c8e43c1d29c 100644
--- net/cookies/cookie_store.h
+++ net/cookies/cookie_store.h
@@ -148,6 +148,11 @@ class NET_EXPORT CookieStore {
   // Transfer ownership of a CookieAccessDelegate.
   void SetCookieAccessDelegate(std::unique_ptr<CookieAccessDelegate> delegate);
 
+  // Adds to the list of cookieable schemes. Does nothing if called after first
+  // use of the instance (i.e. after the instance initialization process).
+  virtual void AddCookieableSchemes(const std::vector<std::string>& schemes,
+                                    SetCookieableSchemesCallback callback) = 0;
+
   // Reports the estimate of dynamically allocated memory in bytes.
   virtual void DumpMemoryStats(base::trace_event::ProcessMemoryDump* pmd,
                                const std::string& parent_absolute_name) const;
diff --git services/network/cookie_manager.cc services/network/cookie_manager.cc
index d1bf7a4d1f6d..772e08ee8916 100644
--- services/network/cookie_manager.cc
+++ services/network/cookie_manager.cc
@@ -228,14 +228,9 @@ void CookieManager::FlushCookieStore(FlushCookieStoreCallback callback) {
 void CookieManager::AllowFileSchemeCookies(
     bool allow,
     AllowFileSchemeCookiesCallback callback) {
-  std::vector<std::string> cookieable_schemes(
-      net::CookieMonster::kDefaultCookieableSchemes,
-      net::CookieMonster::kDefaultCookieableSchemes +
-          net::CookieMonster::kDefaultCookieableSchemesCount);
-  if (allow) {
-    cookieable_schemes.push_back(url::kFileScheme);
-  }
-  cookie_store_->SetCookieableSchemes(cookieable_schemes, std::move(callback));
+  if (!allow)
+    return;
+  cookie_store_->AddCookieableSchemes({url::kFileScheme}, std::move(callback));
 }
 
 void CookieManager::SetForceKeepSessionState() {
diff --git services/network/network_context.cc services/network/network_context.cc
index 5e37a45a033a..ca44461120a8 100644
--- services/network/network_context.cc
+++ services/network/network_context.cc
@@ -1795,6 +1795,7 @@ URLRequestContextOwner NetworkContext::MakeURLRequestContext() {
   }
 
   scoped_refptr<SessionCleanupCookieStore> session_cleanup_cookie_store;
+  std::unique_ptr<net::CookieMonster> cookie_store;
   if (params_->cookie_path) {
     scoped_refptr<base::SequencedTaskRunner> client_task_runner =
         base::ThreadTaskRunnerHandle::Get();
@@ -1821,18 +1822,26 @@ URLRequestContextOwner NetworkContext::MakeURLRequestContext() {
     session_cleanup_cookie_store =
         base::MakeRefCounted<SessionCleanupCookieStore>(sqlite_store);
 
-    std::unique_ptr<net::CookieMonster> cookie_store =
+    cookie_store =
         std::make_unique<net::CookieMonster>(session_cleanup_cookie_store.get(),
                                              net_log);
     if (params_->persist_session_cookies)
       cookie_store->SetPersistSessionCookies(true);
-
-    builder.SetCookieStore(std::move(cookie_store));
   } else {
     DCHECK(!params_->restore_old_session_cookies);
     DCHECK(!params_->persist_session_cookies);
+    cookie_store =
+        std::make_unique<net::CookieMonster>(nullptr /* store */, net_log);
+  }
+
+  if (params_->cookieable_schemes.has_value()) {
+    cookie_store->SetCookieableSchemes(
+        *params_->cookieable_schemes,
+        net::CookieStore::SetCookieableSchemesCallback());
   }
 
+  builder.SetCookieStore(std::move(cookie_store));
+
   if (base::FeatureList::IsEnabled(features::kTrustTokens)) {
     trust_token_store_ = std::make_unique<PendingTrustTokenStore>();
 
diff --git services/network/public/mojom/network_context.mojom services/network/public/mojom/network_context.mojom
index 9515fe92e0b1..e659550debd2 100644
--- services/network/public/mojom/network_context.mojom
+++ services/network/public/mojom/network_context.mojom
@@ -219,6 +219,9 @@ struct NetworkContextParams {
   // cookies. Otherwise it should be false.
   bool persist_session_cookies = false;
 
+  // Schemes that will be passed to CookieMonster::SetCookieableSchemes.
+  array<string>? cookieable_schemes;
+
   // True if an HTTP cache should be used.
   bool http_cache_enabled = true;
   // Maximum size of the HTTP cache. 0 means to use the default size.